Our collaborative paper with Profs. Lin Shixian and He Chuan, “O-GlcNAcylation determines the biological function of YTHDF proteins”, is now published in Nature Cell Biology and highlighted by Nat. Cell Biol. as “O-GlcNAc regulates YTHDF1 and YTHDF3 activity”.
NCB | Glycosylation regulates YTHDF1/3 translation-promoting function and phase separation
Our Nature Cell Biology paper with Profs. Lin Shixian and He Chuan reveals that glycosylation controls YTHDF1/3 translation-promoting activity and phase-separation behaviour.
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2026-08-05Publications
2026-06-11Group
Protein & Cell | O-GlcNAc clusters regulate transcriptional condensates
In collaboration with Prof. Jun Liu's team, we report that O-GlcNAc clusters within disordered regions of transcriptional regulators control the material properties of …
Silan Liu: Breaking the 'sweet armour' — The SMART Choice
Postdoctoral fellow Silan Liu shares the story behind her work on strategies that detect and manipulate cell-surface glycans.